• Extract and analyze sequence information from gene and protein databases.
• Protein-protein interaction analysis.
• Multiple sequence alignments.
• Construct design for protein expression and crystallography
GPRS provides
• Aggregate 3D-structure information.
• Calculate homology models.
• Epitope prediction for mAb generation or vaccine design.
• 3D models to support X-ray structure calculations
Computational Chemistry
You need to know
• Extraction of data from various databases.
• Support in Medicinal Chemistry projects.
• Advise in compound properties optimization; ADMET.
• Experience in epitope mapping, peptide arrays.
GPRS provides
• Analysis of biological screening data and establish a SAR.
• Establish a predictive quantitative structure-activity relationship (QSAR) model.
• Experience in epitope mapping, peptide arrays.
• Guidance in the lead optimization of peptides and macrocyclic compounds.
Drug design
You need to know
• Extract and analysis target structures.
• Elucidate drug and hit 3D-structures.
• Perform docking studies and virtual screening computer calculations.
GPRS provides
• Design of combinatorial compound libraries.
• Suggest new compounds for your patent application.
• Support in the design of protein-protein interaction ligands.
Project management
• Temporary project management.
• Temporary project coordination.
• Acquire offers and contacts to CROs and externals skills.
• Implement project strategy.
• Coaching project managers and team members.
